Mary Halcomb, 23, of Mary Alice, was taken to Harlan Appalachian Regional Hospital after a one-vehicle collision around 10:30 a.m. Friday morning on KY 72 at Pansy.
She was a passenger in a white car driven by Viki West, 43, of Gulston.
According to police, West's car ran off the road, struck a fence, hit a tree and cut a utility pole in half before coming to rest upside down in the front lawn of Pansy Christian Church.
Halcomb received multiple injuries and was extricated by the Harlan County Rescue Squad and taken to HARH by Harlan EMS.
West refused treatment and was charged with third-degree operating a motor vehicle under the influence.
Kentucky State Police trooper Rob Farley is investigating the incident.
Four people were transported to Harlan Appalachian Regional Hospital after a separate three-vehicle collision around 3 p.m. on the intersection of KY 38 and South Main Street.
According to police, Amy Reavis, 21, of Loyall, driving a red 1999 Pontiac Sunfire, was stopped at the intersection about to make a right turn, towards US 421, when she changed her mind and decided to go straight.
In doing so, she pulled into the path of a 1997 Chevy truck, driven by Billy Kelly, 70, of Clospint, clipping the drivers side of his truck and causing him to hit a 2002 Ford Fed-Ex truck, driven by Leroy Fugate, 39, of Perry County.
Reavis' vehicle continued to hit a guard post before coming to rest in the middle of KY 38 facing East. Reavis, and her sister, Hope Reavis, 17, were transported to HARH by LifeCare Ambulance service.
Kelly and his wife, Georgia Kelly, 59, were transported to HARH by Harlan EMS.
All parties were wearing seat belts.
Harlan Police Department officer Mike Thomas is investigating the incident. He was assisted on the scene by Harlan Police officers Marvin Lipfird and Danny Caudill, Harlan Sheriff's officers Eddy Jones and Jayson Howard and members of the Harlan Fire Department.